Scientists Identify Genes Shaping Health, Longevity, and Fertility
Researchers from the Leverhulme Centre for Demographic Science at Oxford University and the University of Iceland have discovered 37 genes that play a significant role in determining health, lifespan, and fertility. By analyzing numerous genetic studies, the team revealed how these genes influence key aspects of human life.
Genes and Reproductive Health
The study found that certain genes dictate the timing of crucial life events, such as the age of first childbirth and the onset of menopause. For instance, the FSHB gene impacts both the start of menstruation and menopause, which are essential for women’s reproductive health. Professor Melinda Mills, the lead researcher, highlighted that this knowledge could greatly assist doctors in addressing infertility and reproductive health challenges, particularly as more couples delay parenthood.
Genetic Links to Disease Risk
Interestingly, some fertility-related genes also affect the likelihood of developing certain diseases, such as breast cancer. Early puberty or late menopause, for example, may increase cancer risk but also contribute to a longer lifespan.
Male Fertility and Genetic Factors
The study also shed light on male fertility. Genes like DNAH2 were found to influence testosterone production and sperm quality, making them crucial for fatherhood.
These groundbreaking findings, published in Nature Aging, offer new insights into the genetic factors shaping human health and open the door to better reproductive health treatments.